A.G.E. Interrupter Advanced

Anti-wrinkle cream

A.G.E. Interrupter Advanced is a potent corrective cream treatment that helps reverse visible signs ... Read full description

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A.G.E. Interrupter Advanced

Anti-wrinkle cream

A.G.E. Interrupter Advanced is a potent corrective cream treatment that helps reverse visible signs of aging impacted by collagen decline and glycation, improving five types of wrinkles frequently targeted for aesthetic procedures.

SKIN TYPES: Dry, Normal, Combination, Sensitive

SKIN CONCERN: Aging

FEATURES:

This next-generation anti-wrinkle cream is formulated with 18% concentrated Proxylane (20% more than previous A.G.E. Interrupter), 4.25% wild fruit flavonoid blend (12.5% more), and new 0.1% glycyrrhetinic acid. This advanced technology is clinically shown to help improve the appearance of five types of wrinkles frequently targeted for aesthetic procedures: forehead wrinkles, glabellar line, crow’s feet, nasolabial folds, and marionette lines.

*Due to the formula’s high levels of flavonoids, this cream's color may vary but will remain effective.

BENEFITS:

Helps reverse visible aging impacted by collagen decline & glycation
Reduces the appearance of five types of visible wrinkles targeted for aesthetic procedures: forehead wrinkles, glabellar lines (“11s”), crow’s feet, nasolabial folds (“smile lines”), and marionette lines
Smooths the appearance of both fine lines and deep wrinkles
Delivers rich, 24-hour hydration, with a luxurious, satin finish
Free of parabens, drying alcohol, and dyes

Twice daily, massage a thin, even layer of A.G.E. Interrupter Advanced wrinkle cream onto the entire face, neck, and chest. If using in the morning, apply after a SkinCeuticals vitamin C antioxidant serum and before a SkinCeuticals sunscreen. If using with a retinol at night, apply after retinol application.

18% Concentrated Proxylane™

Helps support skin’s integrity and correct visible signs of aging, like wrinkles.

4.25% Wild Fruit Flavonoids

Combination of blueberry and pomegranate extracts help reduce oxidative stress, which can be linked to A.G.E. formation, and protect against free radical damage.

.1% GLYCYRRHETINIC ACID

Known to help counter dull tone, which can be linked to A.G.E. accumulation, and is known for its soothing properties.

3% HEPES

Activates natural enzymes in skin to promote even cell turnover while hydrating skin.

1% Niacinamide

Water-soluble vitamin, also known as vitamin B3, soothes and helps support skin’s moisture barrier.

See All Ingredients

AQUA / WATER ●
HYDROXYPROPYL TETRAHYDROPYRANTRIOL ●
GLYCERIN ●
PROPYLENE GLYCOL ●
STEARIC ACID ●
BUTYROSPERMUM PARKII BUTTER / SHEA BUTTER ●
HYDROXYETHYLPIPERAZINE ETHANE SULFONIC ACID ●
PALMITIC ACID ●
PENTYLENE GLYCOL ●
OLEYL ALCOHOL ●
ARACHIDYL ALCOHOL ●
MYRISTYL MYRISTATE ●
PANTHENOL ●
NIACINAMIDE ●
DIMETHICONE ●
ISONONYL ISONONANOATE ●
BIS-PEG/PPG-16/16 PEG/PPG-16/16 DIMETHICONE ●
GLYCERYL STEARATE ●
CANDELILLA CERA / CANDELILLA WAX ●
BEHENYL ALCOHOL ●
PEG-100 STEARATE ●
SODIUM POLYACRYLATE ●
PENTAERYTHRITYL TETRAISOSTEARATE ●
4-T-BUTYLCYCLOHEXANOL ●
ARACHIDYL GLUCOSIDE ●
CAPRYLYL GLYCOL ●
XANTHAN GUM ●
CHLORPHENESIN ●
MYRISTIC ACID ●
CAPRYLIC/CAPRIC TRIGLYCERIDE ●
GLYCYRRHETINIC ACID ●
PARFUM / FRAGRANCE ●
SORBITOL ●
VACCINIUM MYRTILLUS FRUIT EXTRACT ●
POTASSIUM HYDROXIDE ●
ADENOSINE ●
CITRIC ACID ●
PUNICA GRANATUM FRUIT EXTRACT ●
LIMONENE ●
COUMARIN ●
LINALOOL ●
PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE

Collagen and elastin are responsible for skin’s youthful look. While many factors contribute to signs of aging, glycation of these proteins plays a role. This multi-phase process occurs when excess sugar binds to proteins in skin. Oxidative stressors, like UV, pollution, and diet, expedite the reaction, transforming the bound proteins into A.G.E.s—advanced glycation end-products.

A.G.E.s turn flexible proteins brittle, making newly glycated collagen lose its critical regenerative ability. As these degenerated proteins cannot break down to be replaced, skin is ultimately weakened, accelerating signs of visible aging including wrinkles.

A.G.E. Interrupter Advanced is potent corrective anti-wrinkle cream designed to help reverse visible aging impacted by collagen decline and glycation on the face. This potent anti-aging cream treatment features a high-concentration combination of Proxylane, wild fruit flavonoids, glycyrrhetinic acid, HEPES, and niacinamide to improve visible signs of aging such as fine lines and deep wrinkles. All in a luxuriously-textured formula.

In a 12-week study, A.G.E. Interrupter Advanced reduced global fine lines by -14.1% and targeted deep wrinkles by -7.9%.

A.G.E. Interrupter Advanced clinically improved five types of facial wrinkles frequently targeted for aesthetic procedures.

11.5% forehead wrinkles
7.3% glabellar wrinkles
7% crow’s feet
11.2% nasolabial folds
7.9% marionette wrinkles

See Protocol

A 12-week, single-center, clinical study was conducted on 77 females with Fitzpatrick type I-VI, ages 38-70, and mild to moderate global wrinkles, fine lines, lack of laxity, rough skin texture, uneven skin tone, and a dull complexion. A.G.E Interrupter Advanced was used twice daily over face, neck and chest in conjunction of a sunscreen for 12 weeks. Efficacy and tolerance evaluations were conducted at baseline, weeks 4, 8, and 12.

Physician Insights for A.G.E. Interrupter Advanced Anti-Wrinkle Cream

It is crucial to protect existing skin collagen against damage from naturally occurring processes like glycation. A.G.E. Interrupter Advanced in this effort is a true game changer.

While in-office procedures are designed to stimulate the production of new skin collagen, A.G.E. Interrupter Advanced is the perfect at home therapy to accelerate the process and enhance the quality of procedure results.

Dr. Lisa R. Ginn - Skin@LRG, LLC Dermatology and Laser Surgery

FREQUENTLY ASKED QUESTIONS

Answers to Your Frequently Asked A.G.E. Interrupter Advanced Questions

How does A.G.E. Interrupter Advanced differ from the original A.G.E. Interrupter?

Like the original A.G.E. Interrupter, A.G.E. Interrupter Advanced is a wrinkle cream that fights glycation. A.G.E. Interrupter Advanced includes an increased concentration of Proxylane (+20%) and wild fruit flavonoids (+12.5%), as well as new efficacious ingredients, such as glycyrrhetinic acid. The texture of A.G.E. Interrupter Advanced is similar to its predecessor, A.G.E. Interrupter, now with an optimized scent.

Why does A.G.E. Interrupter Advanced have a different color than the previous formula?

A.G.E. Interrupter Advanced features a combination of wild fruit flavonoids (blueberry and pomegranate extracts) that are 12.5% higher than the additional single flavonoid (blueberry extract) used in the original A.G.E. Interrupter formulation. These ingredients can contribute to a slightly pink tone. Further, due to color variances of these naturally-derived ingredients, this formula’s color may also vary, but will remain effective.

How does A.G.E. Interrupter Advanced differ from the original A.G.E. Interrupter?

Like A.G.E. Interrupter, A.G.E. Interrupter Advanced is a wrinkle cream that fights glycation. A.G.E. Interrupter Advanced includes an increased concentration of Proxylane as well as additional efficacious ingredients in glycyrrhetinic acid HEPES that bring forth anti-glycation science and collagen decline reversal. The texture of A.G.E. Interrupter Advanced is the same as A.G.E. Interrupter, but the new formulation does have a different scent.

What does A.G.E. Interrupter Advanced do?

Can I use A.G.E. Interrupter Advanced with retinol?

Does A.G.E. Interrupter Advanced cream get rid of wrinkles?

What is glycation?

Glycation, a major factor of intrinsic and extrinsic aging, occurs when excess sugar molecules bind to collagen and elastin fibers and prompt the formation of advanced glycation end-products (A.G.E.). As a result, glycated collagen and elastin fibers lose the ability to function normally, and the body cannot break them down and replace them, leading to severe wrinkling of the skin.

HOW DOES GLYCATION AGE YOUR SKIN?

An accumulation of the body's natural sugars can damage skin during a reaction called glycation. In this process, sugars bind to the proteins responsible for keeping skin supple, soft and youthful-looking, like collagen and elastin. This forms harmful molecules known as Advanced Glycation End-Products (A.G.E.), which cause protein damage and lead to visible wrinkles, loss of firmness and aging skin.