A.G.E. Interrupter Advanced
A.G.E. Interrupter Advanced is a potent corrective cream treatment that helps reverse visible signs ... Read full description
A.G.E. Interrupter Advanced is a potent corrective cream treatment that helps reverse visible signs of aging impacted by collagen decline and glycation, improving five types of wrinkles frequently targeted for aesthetic procedures.
SKIN TYPES: Dry, Normal, Combination, Sensitive
SKIN CONCERN: Aging
FEATURES:This next-generation anti-wrinkle cream is formulated with 18% concentrated Proxylane (20% more than previous A.G.E. Interrupter), 4.25% wild fruit flavonoid blend (12.5% more), and new 0.1% glycyrrhetinic acid. This advanced technology is clinically shown to help improve the appearance of five types of wrinkles frequently targeted for aesthetic procedures: forehead wrinkles, glabellar line, crow’s feet, nasolabial folds, and marionette lines.
*Due to the formula’s high levels of flavonoids, this cream's color may vary but will remain effective.
BENEFITS:- Helps reverse visible aging impacted by collagen decline & glycation
- Reduces the appearance of five types of visible wrinkles targeted for aesthetic procedures: forehead wrinkles, glabellar lines (“11s”), crow’s feet, nasolabial folds (“smile lines”), and marionette lines
- Smooths the appearance of both fine lines and deep wrinkles
- Delivers rich, 24-hour hydration, with a luxurious, satin finish
- Free of parabens, drying alcohol, and dyes
Twice daily, massage a thin, even layer of A.G.E. Interrupter Advanced wrinkle cream onto the entire face, neck, and chest. If using in the morning, apply after a SkinCeuticals vitamin C antioxidant serum and before a SkinCeuticals sunscreen. If using with a retinol at night, apply after retinol application.
- 18% Concentrated Proxylane™
- 4.25% Wild Fruit Flavonoids
- .1% GLYCYRRHETINIC ACID
- 3% HEPES
- 1% Niacinamide
Helps support skin’s integrity and correct visible signs of aging, like wrinkles.
Combination of blueberry and pomegranate extracts help reduce oxidative stress, which can be linked to A.G.E. formation, and protect against free radical damage.
Known to help counter dull tone, which can be linked to A.G.E. accumulation, and is known for its soothing properties.
Activates natural enzymes in skin to promote even cell turnover while hydrating skin.
Water-soluble vitamin, also known as vitamin B3, soothes and helps support skin’s moisture barrier.
Collagen and elastin are responsible for skin’s youthful look. While many factors contribute to signs of aging, glycation of these proteins plays a role. This multi-phase process occurs when excess sugar binds to proteins in skin. Oxidative stressors, like UV, pollution, and diet, expedite the reaction, transforming the bound proteins into A.G.E.s—advanced glycation end-products.
A.G.E.s turn flexible proteins brittle, making newly glycated collagen lose its critical regenerative ability. As these degenerated proteins cannot break down to be replaced, skin is ultimately weakened, accelerating signs of visible aging including wrinkles.
A.G.E. Interrupter Advanced is potent corrective anti-wrinkle cream designed to help reverse visible aging impacted by collagen decline and glycation on the face. This potent anti-aging cream treatment features a high-concentration combination of Proxylane, wild fruit flavonoids, glycyrrhetinic acid, HEPES, and niacinamide to improve visible signs of aging such as fine lines and deep wrinkles. All in a luxuriously-textured formula.
In a 12-week study, A.G.E. Interrupter Advanced reduced global fine lines by -14.1% and targeted deep wrinkles by -7.9%.
A.G.E. Interrupter Advanced clinically improved five types of facial wrinkles frequently targeted for aesthetic procedures.
- 11.5% forehead wrinkles
- 7.3% glabellar wrinkles
- 7% crow’s feet
- 11.2% nasolabial folds
- 7.9% marionette wrinkles

Physician Insights for A.G.E. Interrupter Advanced Anti-Wrinkle Cream
It is crucial to protect existing skin collagen against damage from naturally occurring processes like glycation. A.G.E. Interrupter Advanced in this effort is a true game changer.
While in-office procedures are designed to stimulate the production of new skin collagen, A.G.E. Interrupter Advanced is the perfect at home therapy to accelerate the process and enhance the quality of procedure results.
Dr. Lisa R. Ginn - Skin@LRG, LLC Dermatology and Laser Surgery
FREQUENTLY ASKED QUESTIONS
Answers to Your Frequently Asked A.G.E. Interrupter Advanced Questions
HOW DOES GLYCATION AGE YOUR SKIN?
An accumulation of the body's natural sugars can damage skin during a reaction called glycation. In this process, sugars bind to the proteins responsible for keeping skin supple, soft and youthful-looking, like collagen and elastin. This forms harmful molecules known as Advanced Glycation End-Products (A.G.E.), which cause protein damage and lead to visible wrinkles, loss of firmness and aging skin.

GLYCATION DOs AND DON'Ts
Help reverse visible aging impacted by collagen decline and glycation
DO
- Protect skin with an antioxidant serum
- Use A.G.E. Interrupter Advanced
- Wear sunscreen
DON'T
- Forget sun protection
- Smoke
- Consume excess sugar and alcohol
